Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002253 | 1.00 | FFAR1 (0.51) | FFAR1ALDH1A1IDO1ARSLC6A2 | |
| SCHEMBL8149379 | 1.00 | FFAR1 (0.51) | FFAR1ALDH1A1IDO1ARSLC6A2 | |
| SCHEMBL7002249 | 1.00 | FFAR1 (0.51) | FFAR1ALDH1A1IDO1ARSLC6A2 | |
| SCHEMBL27426841 | 0.87 | FFAR1 (0.51) | FFAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8152908 | 0.87 | FFAR1 (0.51) | FFAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7003669 | 0.87 | FFAR1 (0.51) | FFAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8152906 | 0.87 | FFAR1 (0.51) | FFAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7003675 | 0.87 | FFAR1 (0.51) | FFAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14301510 | 0.85 | FFAR1 (0.55) | FFAR1ALDH1A1IDO1CYP1A2CYP3A4 | |
| SCHEMBL6999004 | 0.85 | FFAR1 (0.55) | FFAR1ALDH1A1IDO1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999005143-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-02-04 | — | — | WO | disclosed |