Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.51 |
| ▸ | MMP1 | P03956 | 10/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | MMP8 | P22894 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149657 | 1.00 | MMP3 (0.51) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6963435 | 0.90 | MMP3 (0.47) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6963446 | 0.90 | MMP3 (0.47) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6958491 | 0.76 | MMP3 (0.58) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6958497 | 0.76 | MMP3 (0.58) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6954697 | 0.76 | MMP3 (0.45) | MMP3MMP1MMP2 | |
| SCHEMBL6954692 | 0.76 | MMP3 (0.45) | MMP3MMP1MMP2 | |
| SCHEMBL6957803 | 0.74 | MMP3 (0.55) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6957808 | 0.74 | MMP3 (0.55) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6963277 | 0.72 | MMP3 (0.53) | MMP3MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021424-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997048688-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |