Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | VEGFA | P15692 | 4/20 | 0.43 |
| ▸ | FLT1 | P17948 | 4/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149317 | 0.87 | FTO (0.64) | EGLN2FTOEGLN1TLR7VEGFA | |
| SCHEMBL8779266 | 0.86 | EGLN2 (0.70) | EGLN2FTOEGLN1TLR7VEGFA | |
| SCHEMBL8883297 | 0.84 | BRD4 (0.47) | EGLN2FTOEGLN1 | |
| SCHEMBL1509110 | 0.82 | EGLN2 (0.52) | EGLN2FTOEGLN1TLR7GRM4 | |
| SCHEMBL1921385 | 0.82 | EGLN2 (0.65) | EGLN2FTOEGLN1TLR7GRM4 | |
| SCHEMBL25934858 | 0.82 | FTO (0.65) | EGLN2FTOEGLN1TLR7GRM4 | |
| SCHEMBL25934739 | 0.82 | EGLN2 (0.65) | EGLN2FTOEGLN1TLR7VEGFA | |
| SCHEMBL8144511 | 0.82 | EGLN2 (0.58) | EGLN2FTOEGLN1TLR7GRM4 | |
| SCHEMBL8135880 | 0.80 | EGLN2 (0.62) | EGLN2FTOEGLN1TLR7GRM4 | |
| SCHEMBL25934714 | 0.80 | FTO (0.74) | EGLN2FTOEGLN1TLR7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020350-A | 3-hydroxypyridine-2-carboxamidoesters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |