Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL156131 | 1.00 | — | — | |
| SCHEMBL656963 | 0.96 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL18960 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28596120 | 0.92 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL9349701 | 0.92 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL28421467 | 0.92 | — | — | |
| SCHEMBL9232705 | 0.92 | — | — | |
| Water SCHEMBL1542414 | 0.92 | CHRNA7 (0.32) | CHRNA7 | |
| Fluoride SCHEMBL2112417 | 0.92 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL538360 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6027707-A | BASED ON SILICON OR GERMANIUM OXIDE AND OXIDES OF ALUMINUM, IRON, GALLIUM, BORON, TITANIUM, VANADIUM, ZIRCONIUM, MOLYBDENUM, ARSENIC, ANTIMONY, CHROMIUM AND/OR MANGANESE; HYDROREFINING CATALYSTS; HYDROCARBON CONVERSIONS | INSTITUT FRANCAIS DU PETROLE (FR) | 2000-02-22 | — | — | US | claimed |
| US-6027707-A | BASED ON SILICON OR GERMANIUM OXIDE AND OXIDES OF ALUMINUM, IRON, GALLIUM, BORON, TITANIUM, VANADIUM, ZIRCONIUM, MOLYBDENUM, ARSENIC, ANTIMONY, CHROMIUM AND/OR MANGANESE; HYDROREFINING CATALYSTS; HYDROCARBON CONVERSIONS | INSTITUT FRANCAIS DU PETROLE (FR) | 2000-02-22 | — | — | US | disclosed |