Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143943 | 0.77 | SRC (1.00) | SRC | |
| SCHEMBL8149901 | 0.73 | SRC (1.00) | SRC | |
| SCHEMBL8150772 | 0.73 | SRC (1.00) | SRC | |
| SCHEMBL8144522 | 0.71 | SRC (0.67) | SRC | |
| SCHEMBL4489025 | 0.69 | SRC (0.58) | SRCHDAC1HDAC8HDAC6CASP1 | |
| SCHEMBL13818390 | 0.69 | SRC (0.54) | SRCCASP1CASP8 | |
| SCHEMBL13818410 | 0.68 | SRC (0.49) | SRCCASP1CASP8 | |
| SCHEMBL7952607 | 0.68 | SRC (0.85) | SRC | |
| SCHEMBL5903467 | 0.67 | CASP1 (0.67) | SRCCASP1CASP8 | |
| SCHEMBL4484988 | 0.67 | SRC (0.55) | SRCCASP1CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000005246-A1 | THIOAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | HOECHST MARION ROUSSEL (FR) | 2000-02-03 | — | — | WO | claimed |
| WO-2000005246-A1 | THIOAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | HOECHST MARION ROUSSEL (FR) | 2000-02-03 | — | — | WO | disclosed |