Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168520 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL8175311 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL15057584 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL14347087 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL24174680 | 0.91 | CHRM2 (0.41) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL6160832 | 0.90 | DGAT1 (0.41) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL6159675 | 0.90 | DGAT1 (0.41) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL6159678 | 0.90 | DGAT1 (0.41) | CHRM2CHRM3CHRM1DGAT1CHRM4 | |
| SCHEMBL24174898 | 0.85 | CHRM2 (0.44) | CHRM2CHRM3CHRM4MAPK1CYP3A4 | |
| SCHEMBL2839537 | 0.85 | CHRM2 (0.44) | CHRM2CHRM3CHRM4MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119773-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |