SCHEMBL8150299

SCHEMBL8150299

CCCCCCCCCCCCOC1O[C@H](COS(=O)(=O)O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IGF2R P11717 4/20 0.53
MAPK1 P28482 1/20 0.47
FGF1 P05230 3/20 0.46
FGF2 P09038 3/20 0.46
VEGFA P15692 3/20 0.46
HPSE Q9Y251 3/20 0.46
SELP P16109 2/20 0.44
PTN P21246 1/20 0.44
MDK P21741 1/20 0.44
BDNF P23560 1/20 0.44
TLR4 O00206 1/20 0.44
GBA1 P04062 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167667 0.90 HPSE (0.47) IGF2RMAPK1FGF1FGF2VEGFA
SCHEMBL258055 0.84 TLR4 (0.53) VEGFASELPTLR4
SCHEMBL8864321 0.82 IGF2R (0.56) IGF2RMAPK1TLR4GBA1
SCHEMBL5145571 0.82 IGF2R (0.56) IGF2RMAPK1TLR4GBA1
SCHEMBL8864499 0.82 IGF2R (0.56) IGF2RMAPK1TLR4GBA1
SCHEMBL8687950 0.81 IGF2R (0.55) IGF2RMAPK1TLR4GBA1
SCHEMBL8691787 0.81 IGF2R (0.55) IGF2RMAPK1TLR4GBA1
SCHEMBL8686568 0.81 IGF2R (0.55) IGF2RMAPK1TLR4GBA1
SCHEMBL17479942 0.80 GBA1 (0.53) IGF2RMAPK1VEGFASELPGBA1
SCHEMBL20684592 0.80 MAPK1 (0.60) IGF2RMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000302666-A IMPROVER OF SKIN RESILIENCE KAO CORP 2000-10-31 JP disclosed