SCHEMBL258055

SCHEMBL258055

CCCCCCCCCC(CCCCCCC)COC1O[C@H](COS(=O)(=O)O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.53
SELP P16109 7/20 0.51
SELL P14151 5/20 0.51
VEGFA P15692 4/20 0.45
AKT1 P31749 1/20 0.41
CETP P11597 1/20 0.41
SELE P16581 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331511 0.90 GAA (0.42) TLR4SELPSELLVEGFAAKT1
SCHEMBL8331515 0.90 GAA (0.42) TLR4SELPSELLVEGFAAKT1
SCHEMBL258089 0.90 SELP (0.57) TLR4SELPSELLVEGFA
SCHEMBL8150299 0.84 IGF2R (0.53) TLR4SELPVEGFA
SCHEMBL8333751 0.81 SELL (0.59) TLR4SELPSELLCETPSELE
SCHEMBL8334049 0.81 SELL (0.59) TLR4SELPSELLCETPSELE
SCHEMBL15618321 0.81 SELL (0.59) TLR4SELPSELLCETPSELE
SCHEMBL15618389 0.81 SELL (0.59) TLR4SELPSELLCETPSELE
SCHEMBL1573005 0.81 SELL (0.59) TLR4SELPSELLCETPSELE
SCHEMBL15618387 0.81 SELL (0.59) TLR4SELPSELLCETPSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968607-B2 Cosmetics 1-isostearylglycerol-3-Sulfate Sodium Salt, used for constriction of keratinocytes; aging resistance KOA CORPORATION (JP) 2011-06-28 US disclosed
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORPORATION (JP) 2008-09-25 US disclosed
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers KAO CORPORATION (JP) 2004-01-15 US disclosed
EP-1325737-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS Kao Corporation (JP) 2003-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers CUTA, DSG1, OGA TLR4 1588/4885SELP 1887/4885SELL 4413/4885
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS DSG1, CUTA, OGA TLR4 1772/4885SELP 2149/4885SELL 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.