Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144324 | 0.85 | KMT2A (0.58) | MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL8143584 | 0.85 | KMT2A (0.76) | MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL8149613 | 0.84 | MAPT (0.50) | MAPTLMNAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8149456 | 0.84 | KMT2A (0.56) | MAPTLMNAKMT2AALDH1A1RAB9A | |
| SCHEMBL8144325 | 0.84 | KMT2A (0.56) | MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL9324908 | 0.82 | KMT2A (0.72) | MAPTKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL8871897 | 0.81 | KMT2A (0.56) | MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL8872045 | 0.80 | ATM (0.55) | MAPTKMT2AALDH1A1 | |
| SCHEMBL8873242 | 0.80 | KMT2A (0.52) | MAPTKMT2AALDH1A1HTTRAB9A | |
| SCHEMBL8150317 | 0.80 | KMT2A (0.52) | MAPTKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040326-A | 3-deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICALS CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0855182-A1 | 3-Deoxyglucosone production inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0353198-B1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4985453-A | DIABETES TREATMENT | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0353198-A1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |