Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143584 | 0.85 | KMT2A (0.76) | KMT2AMAPTRAB9AALDH1A1F2 | |
| SCHEMBL8144324 | 0.82 | KMT2A (0.58) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8872152 | 0.82 | KMT2A (0.55) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8144325 | 0.81 | KMT2A (0.56) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8149456 | 0.81 | KMT2A (0.56) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8150342 | 0.81 | MAPT (0.68) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8872045 | 0.80 | ATM (0.55) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8872124 | 0.80 | KMT2A (0.65) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8873242 | 0.77 | KMT2A (0.52) | KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8150317 | 0.77 | KMT2A (0.52) | KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681843-A | ANTIDIABETIC; ALDOSE REDUCTASE INHIBITOR WITHOUT SUBSTANTIALLY INHIBITING ALDEHYDE REDUCATASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0718289-A1 | Novel parabanic acid derivatives as aldose reductase inhibitors | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |