Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376577 | 0.81 | EGFR (0.42) | GAATOP1HTTHPGDKDM4E | |
| SCHEMBL3354479 | 0.81 | MAPT (0.40) | MGMTNPY1RMEN1KMT2ATOP1 | |
| SCHEMBL311056 | 0.81 | MGMT (0.59) | MGMTMEN1KMT2AMAPTLMNA | |
| SCHEMBL191388 | 0.80 | MAPT (0.40) | MGMTNPY1RMEN1KMT2AGAA | |
| SCHEMBL8561208 | 0.78 | HPGD (0.43) | MGMTMEN1KMT2AGAAPKM | |
| SCHEMBL3355146 | 0.74 | MAPT (0.38) | MGMTNPY1RMEN1KMT2AGAA | |
| SCHEMBL3357601 | 0.74 | TLR8 (0.38) | MGMTNPY1RMEN1KMT2AMAPT | |
| SCHEMBL6023201 | 0.72 | MAPT (0.39) | NPY1RMEN1KMT2AMAPTLMNA | |
| SCHEMBL4378165 | 0.72 | TLR8 (0.40) | GAATOP1MAPTHPGDKDM4E | |
| SCHEMBL8567046 | 0.72 | HTT (0.47) | MGMTNPY1RMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040112-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999029693-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |