Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191388 | 0.79 | MAPT (0.40) | MAPTTLR8TLR7NPY1RMEN1 | |
| SCHEMBL3355146 | 0.73 | MAPT (0.38) | MAPTTLR8TLR7NPY1RMEN1 | |
| SCHEMBL8150367 | 0.72 | MGMT (0.41) | MAPTNPY1RMEN1KMT2AALDH1A1 | |
| SCHEMBL3357601 | 0.71 | TLR8 (0.38) | MAPTTLR8TLR7NPY1RMEN1 | |
| SCHEMBL17806132 | 0.70 | ALDH1A1 (0.58) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL311056 | 0.70 | MGMT (0.59) | MAPTMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL29603890 | 0.69 | HPGD (0.38) | MAPTKMT2ASMN1; SMN2TP53CYP3A4 | |
| SCHEMBL3354479 | 0.68 | MAPT (0.40) | MAPTNPY1RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5552481 | 0.67 | PDE10A (0.38) | MAPTNPY1RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11973739 | 0.66 | PDE10A (0.53) | MAPTNPY1RMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512685-B1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYTHESIS | MINNESOTA MINING & MFG (US) | 2006-07-19 | — | — | EP | disclosed |