Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685962 | 0.87 | ACE2 (0.45) | ACE2MYCKDM4ETSHRALDH1A1 | |
| SCHEMBL7523843 | 0.85 | ACE2 (0.44) | ACE2TSHRALDH1A1 | |
| SCHEMBL28578080 | 0.84 | ACE2 (0.53) | ACE2MYCKDM4ETSHRALDH1A1 | |
| SCHEMBL815099 | 0.84 | ACE2 (0.51) | ACE2MYCKDM4ETSHRGRM1 | |
| SCHEMBL31315029 | 0.83 | ACE2 (0.49) | ACE2MYCKDM4ETSHRALDH1A1 | |
| SCHEMBL1356395 | 0.83 | ACE2 (0.54) | ACE2MYCKDM4ETSHRALDH1A1 | |
| SCHEMBL29637442 | 0.83 | GRM1 (0.46) | MYCTSHRALDH1A1HCAR3GRM1 | |
| SCHEMBL16897563 | 0.83 | GRM1 (0.46) | MYCTSHRALDH1A1HCAR3GRM1 | |
| SCHEMBL2725195 | 0.81 | ACE2 (0.46) | ACE2MYCKDM4ETSHRGRM1 | |
| SCHEMBL7148262 | 0.81 | ALDH1A1 (0.49) | KDM4EKDM5BALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780340-B1 | Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith | AMCOL INTERNATIONAL CORP (US) | 2002-03-20 | — | — | EP | claimed |
| EP-0747323-B1 | Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same | AMCOL INTERNATIONAL CORP (US) | 2001-12-12 | — | — | EP | claimed |