Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141768 | 0.85 | PTGS1 (0.43) | PTGS1PTGS2MPOKDRCLK2 | |
| SCHEMBL13727966 | 0.81 | MPO (0.46) | MPOHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL17503754 | 0.74 | KDM4C (0.41) | MEN1KMT2AGSK3AGSK3BTSHR | |
| SCHEMBL2174621 | 0.74 | MPO (0.47) | MPOKDM4EALDH1A1GLAGAA | |
| SCHEMBL11472886 | 0.73 | PRNP (0.51) | PTGS1PTGS2ABCC8KCNJ11KDM4E | |
| SCHEMBL2711168 | 0.73 | NT5E (0.50) | MPOKDRCLK2HIPK4SRPK1 | |
| SCHEMBL15483464 | 0.72 | PTGS1 (0.38) | PTGS1PTGS2HTR1AADRA1DADRA1A | |
| SCHEMBL13728331 | 0.72 | KMT2A (0.46) | KDRCLK2HIPK4SRPK1CLK4 | |
| SCHEMBL13728145 | 0.71 | MPO (0.44) | MPOKDRDYRK1AKDM4EALDH1A1 | |
| SCHEMBL13975732 | 0.71 | NPC1 (0.51) | MPOKDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |