Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 8/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CDA | P32320 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033031 | 1.00 | PYGL (0.55) | PYGLSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL8619293 | 0.78 | PYGL (0.63) | PYGLMAPTKDM4EGMNNLMNA | |
| SCHEMBL9239176 | 0.78 | PYGL (0.63) | PYGLMAPTKDM4EGMNNLMNA | |
| SCHEMBL17224208 | 0.77 | PYGL (0.52) | PYGLSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL1031447 | 0.77 | PYGL (0.52) | PYGLSLC28A1SLC28A2SLC29A1SLC28A3 | |
| Ribose (Furanose) SCHEMBL7714783 | 0.76 | SLC28A1 (0.45) | PYGLSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6489385 | 0.76 | PYGL (0.50) | PYGLMAPTKDM4EGMNNLMNA | |
| SCHEMBL4193972 | 0.76 | PYGL (0.50) | PYGLMAPTKDM4EGMNNLMNA | |
| SCHEMBL11284980 | 0.76 | PYGL (0.50) | PYGLMAPTKDM4EGMNNLMNA | |
| SCHEMBL6538568 | 0.75 | PYGL (0.63) | PYGLMAPTKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980424-A2 | ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998050530-A2 | ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-11-12 | — | — | WO | disclosed |