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Arginine

Arginine

SCHEMBL8152157

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.C[C@@H](OC(=O)[C@@H](N)Cc1ccccc1)[C@H](N)C(=O)OC(=O)CN.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](COC(=O)[C@@H](N)Cc1ccc(OC(=O)[C@@H](N)Cc2c[nH]c3ccccc23)cc1)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 15/20 0.38
▸ PTH1R Q03431 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL6482306 0.92 PTH1R (0.40) GLP1RPTH1R
Tryptophan SCHEMBL5820703 0.91 PTH1R (0.39) GLP1RPTH1R
Tryptophan SCHEMBL10623343 0.90 GLP1R (0.39) GLP1RPTH1R
Tryptophan SCHEMBL9295342 0.90 PTH1R (0.40) GLP1RPTH1R
Tryptophan SCHEMBL10619278 0.88 GLP1R (0.41) GLP1RPTH1R
Phenylalanine SCHEMBL6479234 0.87 GLP1R (0.35) GLP1RPTH1R
Tryptophan SCHEMBL9614424 0.87 PTH1R (0.39) GLP1RPTH1R
Phenylalanine SCHEMBL6563941 0.87 GLP1R (0.34) GLP1RPTH1R
Tryptophan SCHEMBL9152334 0.87 PTH1R (0.42) GLP1RPTH1R
Phenylalanine SCHEMBL6438432 0.86 GLP1R (0.34) GLP1RPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1003469-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2000-05-31 — — EP disclosed
WO-1997030687-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-08-28 — — WO disclosed