Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152868 | 0.93 | PPARG (0.46) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8157085 | 0.87 | TDP1 (0.43) | ALOX5APEX1TDP1POLBHTT | |
| SCHEMBL8381808 | 0.87 | TDP1 (0.43) | ALOX5APEX1TDP1POLBHTT | |
| SCHEMBL8143834 | 0.83 | APEX1 (0.36) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8151997 | 0.83 | APEX1 (0.38) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8152091 | 0.82 | APEX1 (0.36) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8152330 | 0.81 | CYP3A4 (0.46) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL9340619 | 0.81 | CYP3A4 (0.46) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8156581 | 0.80 | POLB (0.47) | PPARGPTGESALOX5APEX1TDP1 | |
| SCHEMBL8150699 | 0.80 | MAPT (0.43) | APEX1TDP1POLBHTTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |