Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152330 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2C9KMT2ARECQLMEN1 | |
| SCHEMBL8157309 | 0.89 | CA1 (0.40) | CYP3A4CYP2C9KMT2ARECQLMEN1 | |
| SCHEMBL8157079 | 0.88 | MEN1 (0.46) | CYP2C9KMT2AMEN1AKR1C3APEX1 | |
| SCHEMBL8153430 | 0.88 | GRIK1 (0.46) | CYP3A4CYP2C9AKR1C3APEX1HTT | |
| SCHEMBL8380576 | 0.88 | GRIK1 (0.46) | CYP3A4CYP2C9AKR1C3APEX1HTT | |
| SCHEMBL8144639 | 0.87 | TBXAS1 (0.40) | CYP3A4CYP2C9KMT2AMEN1AKR1C3 | |
| SCHEMBL8157085 | 0.87 | TDP1 (0.43) | KMT2AAKR1C3APEX1HTTPOLB | |
| SCHEMBL8381808 | 0.87 | TDP1 (0.43) | KMT2AAKR1C3APEX1HTTPOLB | |
| SCHEMBL8151236 | 0.86 | PTGS2 (0.44) | CYP2C9KMT2AMEN1AKR1C3APEX1 | |
| SCHEMBL8143779 | 0.86 | MAPT (0.46) | KMT2AMEN1AKR1C3APEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600064-A1 | OPTICAL NON-LINEAR POLYMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| WO-1994000797-A1 | OPTICAL NON-LINEAR POLYMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-06 | — | — | WO | disclosed |