Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978232 | 0.85 | CHEK1 (0.36) | LMNASIGMAR1HTTNPSR1TP53 | |
| SCHEMBL6982438 | 0.85 | PIK3R1 (0.39) | HPGDHTTNPSR1MAPTMAPK1 | |
| SCHEMBL8157626 | 0.80 | POLB (0.36) | LMNAHTTNPSR1TP53MAPT | |
| SCHEMBL6983094 | 0.77 | MAOB (0.33) | PIK3R1PIK3CAKMT2AMEN1 | |
| SCHEMBL6983135 | 0.77 | PTGDR2 (0.39) | KMT2AMEN1 | |
| SCHEMBL6971985 | 0.77 | SMN1; SMN2 (0.43) | LMNAHPGDNPSR1CYP3A4MAPK1 | |
| SCHEMBL6979976 | 0.75 | SMN1; SMN2 (0.34) | LMNAHTTNPSR1MAPTPIK3R1 | |
| SCHEMBL8157787 | 0.75 | MAOB (0.44) | HPGDHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7083107 | 0.75 | IDO1 (0.33) | LMNASIGMAR1MAPTMAPK1 | |
| SCHEMBL7971630 | 0.73 | EGLN1 (0.33) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |