Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978806 | 0.87 | GRM2 (0.41) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL6983135 | 0.84 | PTGDR2 (0.39) | MEN1KMT2A | |
| SCHEMBL6983094 | 0.82 | MAOB (0.33) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL7087746 | 0.82 | MAOA (0.33) | MAOBMAOA | |
| SCHEMBL7083107 | 0.80 | IDO1 (0.33) | MAOBMAOA | |
| SCHEMBL6982438 | 0.79 | PIK3R1 (0.39) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL6978232 | 0.78 | CHEK1 (0.36) | CHEK1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6979976 | 0.77 | SMN1; SMN2 (0.34) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6971985 | 0.76 | SMN1; SMN2 (0.43) | MEN1KMT2ACA12CA9ALDH1A1 | |
| SCHEMBL6981400 | 0.75 | PSEN1 (0.39) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |