Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367281 | 0.84 | MEN1 (0.54) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7041242 | 0.77 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5294666 | 0.71 | MEN1 (0.70) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7106841 | 0.71 | KDM4E (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7334978 | 0.70 | CHKA (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5371333 | 0.70 | MEN1 (0.54) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL3713633 | 0.69 | MEN1 (0.71) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL2478090 | 0.69 | PRKDC (0.58) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8931737 | 0.69 | DRD4 (0.67) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5242737 | 0.68 | MEN1 (0.70) | MAPTALDH1A1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |