Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 8/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160892 | 0.99 | HSD17B10 (0.60) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8155805 | 0.99 | HSD17B10 (0.60) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8154750 | 0.96 | TSHR (0.51) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL14526076 | 0.93 | TSHR (0.59) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL9240972 | 0.93 | HSD17B10 (0.49) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL15783717 | 0.91 | TSHR (0.61) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8146455 | 0.90 | DAO (0.49) | TSHRHSD17B10DAOTRPV4MEN1 | |
| SCHEMBL14526069 | 0.88 | TSHR (0.53) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL11963202 | 0.88 | TRPV4 (0.50) | TSHRHSD17B10DAOTRPV4HTR2A | |
| SCHEMBL8161286 | 0.87 | TSHR (0.47) | TSHRHSD17B10RARBRARADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36849-E | 2-(4-(ALK(EN)YL, ALKOXY, ALKANOYL)-4'-BICYCLOHEXYL)-1-(2,3-(HALO OR NITRILE),4-HALOPHENYL)ETHANE COMPOUNDS; ELECTROOPTICAL DISPLAY WITH MULTIPLEX OPERATION COMPRISING A LIQUID CRYSTAL MIXTURE AS DIELECTRIC | MERCK PATENT GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0452460-B2 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK PATENT GMBH (DE) | 1999-08-11 | — | — | EP | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |
| US-4710315-A | USE WITH MULTIPLEXIBLE DISPLAYS HAVING HIGH DENSITY IMAGES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-01 | — | — | US | disclosed |