Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175911 | 1.00 | PREP (0.34) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7294072 | 0.94 | — | — | |
| SCHEMBL9047518 | 0.91 | GBA1 (0.32) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9050007 | 0.91 | GBA1 (0.32) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9051048 | 0.89 | GBA1 (0.35) | — | |
| SCHEMBL9047663 | 0.89 | GBA1 (0.35) | — | |
| SCHEMBL9049381 | 0.88 | GBA1 (0.38) | — | |
| SCHEMBL9048296 | 0.87 | KMT2A (0.31) | — | |
| SCHEMBL9050045 | 0.85 | PREP (0.30) | PREP | |
| SCHEMBL9048597 | 0.84 | FAAH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |