Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796831 | 0.89 | CA1 (0.56) | CA1CA2CA9KDM4EUSP2 | |
| Phosphonic Acid SCHEMBL8153846 | 0.78 | KDM4E (0.36) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9400151 | 0.75 | CA1 (0.52) | CA1CA2CA9HTT | |
| SCHEMBL14844857 | 0.74 | USP2 (0.43) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL2170402 | 0.74 | USP2 (0.43) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL23674320 | 0.72 | USP2 (0.42) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL1965705 | 0.72 | USP2 (0.42) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL15083764 | 0.71 | ALDH1A1 (0.37) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL6256083 | 0.71 | KDM4E (0.37) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL775983 | 0.70 | CA1 (0.65) | CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000510455-A | — | — | 2000-08-15 | — | — | JP | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | claimed |
| WO-1997039756-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | TROPONWERKE GMBH & CO. KG (DE) | 1997-10-30 | — | — | WO | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |