Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | PGK2 | P07205 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylphosphonic Acid SCHEMBL44318 | 0.80 | HPGD (0.60) | HPGDTSHRLAP3ANPEPACP3 | |
| SCHEMBL497159 | 0.80 | HPGD (0.60) | HPGDTSHRFDPSLAP3ANPEP | |
| SCHEMBL3080168 | 0.79 | HPGD (0.54) | HPGDTSHRFDPSLAP3ANPEP | |
| SCHEMBL6310521 | 0.78 | HPGD (0.58) | HPGDTSHRFDPSLAP3ANPEP | |
| Benzylphosphonic Acid SCHEMBL11339355 | 0.78 | HPGD (0.58) | HPGDTSHRLAP3ANPEPACP3 | |
| Benzylphosphonic Acid SCHEMBL9182484 | 0.78 | HPGD (0.58) | HPGDTSHRLAP3ANPEPACP3 | |
| Benzylphosphonic Acid SCHEMBL915222 | 0.78 | HPGD (0.58) | HPGDTSHRLAP3ANPEPACP3 | |
| SCHEMBL17004009 | 0.78 | HPGD (0.58) | HPGDTSHRFDPSLAP3ANPEP | |
| Benzylphosphonic Acid SCHEMBL5332218 | 0.78 | HPGD (0.58) | HPGDTSHRLAP3ANPEPACP3 | |
| Benzylphosphonic Acid SCHEMBL11474641 | 0.78 | HPGD (0.58) | HPGDTSHRLAP3ANPEPACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957924-A4 | CERTAIN PHOSPHINYL DERIVATIVES USEFUL AS NAALADASE INHIBITORS | GUILFORD PHARM INC (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0957924-A1 | CERTAIN PHOSPHINYL DERIVATIVES USEFUL AS NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997048399-A1 | CERTAIN PHOSPHINYL DERIVATIVES USEFUL AS NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | disclosed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | disclosed |