Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 11/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.46 |
| ▸ | PRKCB | P05771 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | PRKCH | P24723 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 2/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149363 | 0.90 | ZAP70 (0.59) | ZAP70CCNT1CDK9PRKD3PRKCG | |
| SCHEMBL8153192 | 0.83 | BRAF (0.46) | ZAP70CCNT1CDK9PRKD3PRKCG | |
| SCHEMBL6956773 | 0.76 | ZAP70 (1.00) | ZAP70CDK9PRKD3PRKCGPRKCB | |
| SCHEMBL6957436 | 0.71 | ZAP70 (0.66) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL8154077 | 0.69 | ZAP70 (0.61) | ZAP70CCNT1CDK9PRKD3PRKCG | |
| SCHEMBL6956423 | 0.69 | ZAP70 (0.68) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL8148269 | 0.69 | ZAP70 (0.62) | ZAP70CCNT1CDK9PRKD3PRKCG | |
| SCHEMBL8139875 | 0.69 | ZAP70 (0.62) | ZAP70CCNT1CDK9PRKD3PRKCG | |
| SCHEMBL609202 | 0.67 | IKBKB (0.69) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL6956788 | 0.67 | ZAP70 (0.82) | ZAP70CDK9PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093716-A | Substituted 2-pyrimidineamines and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 2000-07-25 | — | — | US | disclosed |