Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146626 | 0.91 | CRHR1 (0.36) | CRHR1SUV39H2TSHR | |
| SCHEMBL8152497 | 0.90 | CRHR1 (0.35) | CRHR1SUV39H2 | |
| SCHEMBL8148200 | 0.88 | TSHR (0.38) | CRHR1SUV39H2TSHR | |
| SCHEMBL8151719 | 0.81 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL8139794 | 0.80 | CRHR1 (0.40) | CRHR1SUV39H2 | |
| SCHEMBL8152915 | 0.78 | CRHR1 (0.34) | CRHR1SUV39H2TSHR | |
| SCHEMBL8147374 | 0.78 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL8152412 | 0.78 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL8149046 | 0.78 | TSHR (0.39) | CRHR1TSHR | |
| SCHEMBL8148157 | 0.77 | CRHR1 (0.36) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994877-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Du Pont Pharmaceuticals Company (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001454-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |