Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160467 | 0.91 | ACKR3 (0.32) | NFE2L2ALDH1A1GAAMAPK1 | |
| SCHEMBL8160944 | 0.86 | NFE2L2 (0.33) | NFE2L2IKBKBCHUKIKBKGALDH1A1 | |
| SCHEMBL8167694 | 0.81 | NFE2L2 (0.33) | NFE2L2IKBKBCHUKIKBKGALDH1A1 | |
| SCHEMBL8159967 | 0.77 | NFE2L2 (0.32) | NFE2L2IKBKBCHUKIKBKG | |
| SCHEMBL8161438 | 0.74 | IKBKB (0.35) | NFE2L2IKBKBCHUKIKBKG | |
| SCHEMBL8161449 | 0.74 | NFE2L2 (0.33) | NFE2L2IKBKBCHUKIKBKG | |
| SCHEMBL8167709 | 0.74 | IKBKB (0.36) | NFE2L2IKBKBCHUKIKBKGMAPK1 | |
| SCHEMBL8161064 | 0.73 | NFE2L2 (0.33) | NFE2L2IKBKBCHUKIKBKG | |
| SCHEMBL8162255 | 0.73 | NFE2L2 (0.33) | NFE2L2IKBKBCHUKIKBKGALDH1A1 | |
| SCHEMBL8162744 | 0.72 | NFE2L2 (0.32) | NFE2L2IKBKBCHUKIKBKG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153793-A2 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |