Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.31 |
| ▸ | HTR3B | O95264 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1217644 | 0.96 | GAA (0.45) | GAAKDM4ECYP3A4TDP1TSHR | |
| SCHEMBL8155129 | 0.84 | TSHR (0.44) | GAACYP3A4TDP1TSHRALDH1A1 | |
| SCHEMBL9333180 | 0.82 | KDM4E (0.58) | GAAKDM4ECYP3A4TDP1ESR1 | |
| SCHEMBL9333200 | 0.82 | KDM4E (0.58) | GAAKDM4ECYP3A4TDP1ESR1 | |
| SCHEMBL2846416 | 0.80 | TDP1 (0.55) | GAAKDM4ECYP3A4TDP1ESR1 | |
| SCHEMBL8674118 | 0.79 | GRM5 (0.37) | GAAKDM4ECYP3A4TSHRALDH1A1 | |
| SCHEMBL1217571 | 0.75 | KDM4E (0.50) | GAAKDM4ECYP3A4TDP1TSHR | |
| SCHEMBL8160391 | 0.75 | KDM4E (0.50) | GAAKDM4ECYP3A4TDP1ESR1 | |
| SCHEMBL8153465 | 0.72 | CYP3A4 (0.41) | GAAKDM4ECYP3A4TDP1TSHR | |
| SCHEMBL1219299 | 0.71 | KDM4E (0.45) | GAAKDM4ECYP3A4TDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386833-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-12 | — | — | EP | claimed |
| EP-0696474-B1 | Catalytic systems and methods for carbonylation | DAICEL CHEM (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0948999-A1 | Catalytic systems and method for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0386833-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1999-06-16 | — | — | EP | disclosed |
| US-5869738-A | OF AN OLEFIN WITH CARBON MONOXIDE PRODUCING AN ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5731255-A | GROUP VIII METAL SOURCE, LIGAND, ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0696474-A2 | Catalytic systems and methods for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0441447-B1 | Carbonylation catalyst process | SHELL INT RESEARCH (NL) | 1994-11-30 | — | — | EP | disclosed |
| EP-0441446-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| EP-0441445-B1 | Preparation of amides | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| US-5166116-A | Coordination catalysts of phosphine, group 8 metal, protons and sulfonate | SHELL OIL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| US-5166411-A | Group 8 metal, a phosphine, a proton source and a tertiary amine | SHELL OIL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| US-5158921-A | Catalyst system which contains palladium compound and phosphine | SHELL OIL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5128475-A | PREPARATION OF AMIDES | SHELL OIL COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5124300-A | Group 8 metal, aromatic phosphine, proton source, tertiary amine | SHELL OIL COMPANY (US) | 1992-06-23 | — | — | US | disclosed |
| US-5099062-A | Reaction of acetylenic compound with carbon monoxide to form unsaturated monomers | SHELL OIL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0441446-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441447-A1 | Carbonylation catalyst process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441445-A2 | Preparation of amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0386833-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-12 | — | — | EP | disclosed |