SCHEMBL1219299

SCHEMBL1219299

Brc1cccc(P(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
KDR P35968 1/20 0.32
KDM1A O60341 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160391 0.96 KDM4E (0.50) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL954853 0.84 HTR7 (0.33) ALDH1A1HPGDGRIN2DGRIN3BGRIN1
SCHEMBL2846416 0.84 TDP1 (0.55) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL9333200 0.82 KDM4E (0.58) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL9333180 0.82 KDM4E (0.58) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL231108 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL5843107 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1219243 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1217002 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1217644 0.75 GAA (0.45) KDM4EGAACYP3A4TDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136884-A Nalfurorphine Process for the preparation of intermediates 江苏杜瑞制药有限公司 2025-06-13 CN claimed
CN-120136884-A Nalfurorphine Process for the preparation of intermediates 江苏杜瑞制药有限公司 2025-06-13 CN disclosed
EP-2256102-B1 PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-09-26 EP disclosed
US-20180026206-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-25 US disclosed
WO-2017063727-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-04-20 WO disclosed
EP-2828232-B1 PROCESS FOR PRODUCING ALKYL METHACRYLATE SUMITOMO CHEMICAL CO (JP) 2016-04-20 EP disclosed
CN-103554183-A Synthetic method and application of novel multi-aryl bridged long-chain diphosphine ligand UNIV NANKAI 2014-02-05 CN disclosed
US-8399699-B2 Process for production of alkoxycarbonyl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed
US-20120214999-A1 METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-23 US disclosed
EP-2487179-A1 METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE Sumitomo Chemical Co., Ltd (JP) 2012-08-15 EP disclosed
EP-2207783-A1 METHOD FOR HYDROFORMYLATION BASF SE (DE) 2010-07-21 EP disclosed
WO-2009059963-A1 METHOD FOR HYDROFORMYLATION BASF SE (DE) 2009-05-14 WO disclosed
EP-0696474-B1 Catalytic systems and methods for carbonylation DAICEL CHEM (JP) 2000-05-17 EP disclosed
EP-0948999-A1 Catalytic systems and method for carbonylation DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-10-13 EP disclosed
US-5869738-A OF AN OLEFIN WITH CARBON MONOXIDE PRODUCING AN ACID DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-09 US disclosed
EP-0724558-B1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INT RESEARCH (NL) 1998-04-29 EP disclosed
US-5731255-A GROUP VIII METAL SOURCE, LIGAND, ACID DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0724558-A1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-08-07 EP disclosed
EP-0696474-A2 Catalytic systems and methods for carbonylation DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-14 EP disclosed
WO-1995005357-A1 PROCESS FOR THE CARBONYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180026206-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 KDM4E 3119/4885GAA 1995/4885CYP3A4 8/4885
US-20120214999-A1 METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE AP1M1, MPHOSPH6, MACO1 KDM4E 666/4885GAA 3765/4885CYP3A4 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.