Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852543 | 1.00 | HSP90AA1 (0.47) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| SCHEMBL8883080 | 1.00 | HSP90AA1 (0.47) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| SCHEMBL8884159 | 0.86 | NPC1 (0.56) | HSP90AA1MITFCCR6ACHEPAX8 | |
| SCHEMBL8884151 | 0.86 | NPC1 (0.56) | HSP90AA1MITFCCR6ACHEPAX8 | |
| SCHEMBL6860704 | 0.79 | HSP90AA1 (0.74) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| SCHEMBL9046529 | 0.79 | MAPT (0.47) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| SCHEMBL5170428 | 0.79 | HSP90AA1 (0.74) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| SCHEMBL9046525 | 0.79 | MAPT (0.47) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| Hydrochloric Acid SCHEMBL1524313 | 0.78 | HSP90AA1 (0.76) | HSP90AA1MITFAKR1C3AKR1C1CCR6 | |
| Hydrochloric Acid SCHEMBL28786402 | 0.78 | HSP90AA1 (0.76) | HSP90AA1MITFAKR1C3AKR1C1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751111-B1 | Process for preparing 2,2-dialkylaryliden-cycloalkanones | BAYER AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| US-5663447-A | Process for the preparation of 2,2 dialkyl-arylidene-cycloalkanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0751111-A2 | Process for preparing 2,2-dialkylaryliden-cycloalkanones | BAYER AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0378953-A1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE-POULENC AGROCHIMIE (FR) | 1990-07-25 | — | — | EP | disclosed |