Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884159 | 1.00 | NPC1 (0.56) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL8852543 | 0.86 | HSP90AA1 (0.47) | NPC1ALDH1A1HSP90AA1MITFACHE | |
| SCHEMBL8883080 | 0.86 | HSP90AA1 (0.47) | NPC1ALDH1A1HSP90AA1MITFACHE | |
| SCHEMBL8154561 | 0.86 | HSP90AA1 (0.47) | NPC1ALDH1A1HSP90AA1MITFACHE | |
| SCHEMBL6860627 | 0.79 | HSP90AA1 (0.74) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL5172642 | 0.79 | HSP90AA1 (0.74) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL6868001 | 0.71 | HSP90AA1 (0.63) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL5169484 | 0.71 | HSP90AA1 (0.63) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL5170295 | 0.70 | HSP90AA1 (0.62) | NPC1ALDH1A1HSD11B1HSP90AA1MITF | |
| SCHEMBL6865054 | 0.70 | HSP90AA1 (0.62) | NPC1ALDH1A1HSD11B1HSP90AA1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |