Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141974 | 1.00 | CCNT1 (0.52) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL30831604 | 1.00 | CCNT1 (0.52) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| Ammonia Solution, Strong SCHEMBL1121071 | 0.98 | CCNT1 (0.51) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL28135263 | 0.93 | CYP1A2 (0.51) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL27534760 | 0.85 | CCNT1 (0.49) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL1445133 | 0.82 | CCNT1 (0.60) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL10601314 | 0.80 | MAPK9 (0.43) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL2039527 | 0.79 | SMN1; SMN2 (0.62) | CYP1A2HSD17B10ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL29496935 | 0.79 | SMN1; SMN2 (0.62) | CYP1A2HSD17B10ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL1880930 | 0.78 | MAPK14 (0.56) | CCNT1CCNA2CDK2CDK9CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114158-A1 | IMIDE-CONTAINING POLYOLS, METHOD FOR MAKING IMIDE-CONTAINING POLYOLS AND METHOD FOR USING THE IMIDE POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-109734708-A | Pyrimidine indoles Nur77 receptor modulators and its preparation method and application | 厦门大学 | 2019-05-10 | — | — | CN | disclosed |
| WO-2014074661-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHα RESPONSES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | WO | disclosed |
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | disclosed |
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |