Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415262 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL10458150 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL10429017 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL16444659 | 0.75 | SMN1; SMN2 (0.32) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8492940 | 0.74 | — | — | |
| Ethyl Acetate SCHEMBL27402814 | 0.72 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL311876 | 0.71 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL4688208 | 0.71 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL36403 | 0.71 | — | — | |
| SCHEMBL10530231 | 0.71 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518294-B2 | Compositions comprising 2,3,3,3-tetrafluoropropene, 2-chloro-2,3,3,3-tetrafluoropropanol, 2-chloro-2,3,3,3-tetrafluoro-propyl acetate or zinc (2-chloro-2,3,3,3-tetrafluoropropdxy) chloride | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-27 | — | — | US | disclosed |
| US-8299309-B2 | Synthesis of hydrofluoroalkanols and hydrofluoroalkenes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20120168672-A1 | COMPOSITIONS COMPRISING 2,3,3,3-TETRAFLUOROPROPENE, 2-CHLORO-2,3,3,3-TETRAFLUOROPROPANOL, 2-CHLORO-2,3,3,3-TETRAFLUORO-PROPYL ACETATE OR ZINC (2-CHLORO-2,3,3,3-TETRAFLUOROPROPOXY) CHLORIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120083619-A1 | Synthesis of Hydrofluoroalkanols and Hydrofluoroalkenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-05 | — | — | US | disclosed |
| US-8147710-B2 | Compositions comprising 2,3,3,3-tetrafluoropropene, 2-chloro-2,3,3,3-tetrafluoropropanol, 2-chloro-2,3,3,3-tetrafluoro-propyl acetate or zinc (2-chloro-2,3,3,3-tetrafluoropropoxy) chloride | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-03 | — | — | US | disclosed |
| US-8058488-B2 | Synthesis of hydrofluoroalkanols and hydrofluoroalkenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-15 | — | — | US | disclosed |
| US-20100090156-A1 | COMPOSITIONS COMPRISING 2,3,3,3-TETRAFLUOROPROPENE, 2-CHLORO-2,3,3,3-TETRAFLUOROPROPANOL, 2-CHLORO-2,3,3,3-TETRAFLUORO-PROPYL ACETATE OR ZINC (2-CHLORO-2,3,3,3-TETRAFLUOROPROPOXY) CHLORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-15 | — | — | US | disclosed |
| US-20090143604-A1 | Synthesis of hydrofluoroalkanols and hydrofluoroalkenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-04 | — | — | US | disclosed |