Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153328 | 0.89 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8141005 | 0.88 | GRIN2D (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8642189 | 0.76 | — | — | |
| SCHEMBL8645781 | 0.73 | ANPEP (0.37) | METAP1ANPEPERAP2 | |
| SCHEMBL8643107 | 0.72 | ANPEP (0.40) | METAP1ANPEPERAP2 | |
| SCHEMBL8152905 | 0.72 | ANPEP (0.40) | METAP1ANPEPERAP2 | |
| SCHEMBL8153189 | 0.68 | CA1 (0.33) | ANPEPERAP2 | |
| SCHEMBL14639770 | 0.67 | CA1 (0.40) | — | |
| SCHEMBL21074754 | 0.67 | CA1 (0.40) | — | |
| SCHEMBL14781411 | 0.67 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |