Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669188 | 0.89 | SPHK1 (0.40) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL4346836 | 0.89 | SPHK1 (0.40) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL4346843 | 0.89 | SPHK1 (0.40) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL25320445 | 0.87 | PSMD10 (0.37) | KMT2APSMD10 | |
| SCHEMBL30695351 | 0.86 | SPHK1 (0.38) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL26782491 | 0.83 | ELANE (0.42) | — | |
| SCHEMBL31362884 | 0.82 | SPHK1 (0.36) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL2332146 | 0.80 | SPHK1 (0.35) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL2332152 | 0.80 | SPHK1 (0.35) | GPR119SPHK1BRD4MEN1KMT2A | |
| SCHEMBL2332163 | 0.80 | SPHK1 (0.35) | GPR119SPHK1BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |