Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155257 | 1.00 | GAA (0.34) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL119997 | 0.89 | KMT2A (0.37) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL32678199 | 0.89 | KMT2A (0.37) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL119998 | 0.89 | KMT2A (0.37) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL959562 | 0.89 | KMT2A (0.37) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL29870686 | 0.89 | KMT2A (0.37) | GAALMNAPOLBALDH1A1HTR2A | |
| SCHEMBL8149111 | 0.84 | LMNA (0.38) | GAALMNAHTR2AMAOBMAPT | |
| SCHEMBL8149110 | 0.84 | LMNA (0.38) | GAALMNAHTR2AMAOBMAPT | |
| SCHEMBL8147257 | 0.82 | TSHR (0.33) | GAAALDH1A1KDM4E | |
| SCHEMBL8147682 | 0.82 | TDP1 (0.37) | GAALMNAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057352-A | CONTROLLING PLANT DISEASES CAUSED BY FUNGAL PLANT PATHOGENS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | claimed |