SCHEMBL8155376

SCHEMBL8155376

C=C(C)C(=O)C(C)OC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 3/20 0.38
LMNA P02545 3/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28080157 0.81 TSHR (0.48) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL6695785 0.79 TSHR (0.45) TDP1TSHRALDH1A1
SCHEMBL4962596 0.76 TSHR (0.38) TSHRLMNAMAPTALDH1A1
SCHEMBL8601903 0.76 HCAR2 (0.43) TSHRALDH1A1
SCHEMBL28617868 0.75
SCHEMBL2105771 0.75
SCHEMBL9639072 0.75 TSHR (0.39) TDP1TSHRALDH1A1
SCHEMBL8213558 0.75 TSHR (0.37) TSHRLMNACHRM2CHRM4CHRM5
SCHEMBL29120908 0.74 TSHR (0.37) TDP1TSHRLMNACHRM2CHRM4
SCHEMBL29120919 0.74 TSHR (0.37) TDP1TSHRLMNACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689712-B Thickening anionic copolymers 可泰克斯公司 2022-01-04 CN claimed
CN-102282220-B Process to prepare self-binding pigment particles implementing acrylic comb copolymers with hydrophobic groups as coupling agents, self binding pigment particles and uses thereof OMYA DEVELOPMENT AG 2014-05-14 CN claimed
CN-101627091-B Method for dry-grinding one or more mineral materials consisting of at least one calcium carbonate OMYA DEV AG CH 2013-11-20 CN claimed
CN-102282220-A Process to prepare self-binding pigment particles implementing acrylic comb copolymers with hydrophobic groups as coupling agents, self binding pigment particles and uses thereof 2011-12-14 CN claimed
CN-101627091-A Method for dry-grinding one or more mineral materials consisting of at least one calcium carbonate OMYA DEVELOPMENT AG 2010-01-13 CN claimed
JP-61275366-A None JP disclosed
CN-108026321-B Plasticizer for acrylic adhesives and binders 道达尔销售服务公司 2020-10-16 CN disclosed
CN-105237690-A HASE-type polymer COATEX SAS 2016-01-13 CN disclosed
CN-102770406-B Associative monomers based on oxo alcohols, acrylic polymers comprising them, use of said polymers as thickeners in aqueous formulations, and resulting formulations COATEX S.A.S. (FR) 2015-10-07 CN disclosed
CN-102282220-B Process to prepare self-binding pigment particles implementing acrylic comb copolymers with hydrophobic groups as coupling agents, self binding pigment particles and uses thereof OMYA DEVELOPMENT AG 2014-05-14 CN disclosed
CN-101627091-B Method for dry-grinding one or more mineral materials consisting of at least one calcium carbonate OMYA DEV AG CH 2013-11-20 CN disclosed
CN-102770406-A Associative monomers based on oxo alcohols, acrylic polymers comprising them, use of said polymers as thickeners in aqueous formulations, and resulting formulations COATEX SAS 2012-11-07 CN disclosed
CN-102282220-A Process to prepare self-binding pigment particles implementing acrylic comb copolymers with hydrophobic groups as coupling agents, self binding pigment particles and uses thereof 2011-12-14 CN disclosed
CN-101627091-A Method for dry-grinding one or more mineral materials consisting of at least one calcium carbonate OMYA DEVELOPMENT AG 2010-01-13 CN disclosed
CN-100558771-C Copolymer having at least one alkoxy-or hydroxy-polyalkylene glycol graft function and use thereof OMYA AG (CH) 2009-11-11 CN disclosed
CN-1717424-A Copolymer having at least one alkoxy- or hydroxy-polyalkylene glycol grafted function, and use thereof OMYA AG (CH) 2006-01-04 CN disclosed
JP-2000186122-A ORGANIC POLYSILOXANE-MODIFIED GRAFT COPOLYMER DOW CORNING CORP 2000-07-04 JP disclosed
JP-S61275366-A COATING COMPOSITION AND COATED MOLDING NIPPON PAINT CO LTD 1986-12-05 JP disclosed