Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155376 | 0.75 | TDP1 (0.42) | TSHRALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL14440872 | 0.72 | — | — | |
| SCHEMBL230496 | 0.67 | ALDH1A1 (0.52) | TSHRALDH1A1MAPT | |
| SCHEMBL2926510 | 0.67 | MCL1 (0.43) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL20706521 | 0.67 | ALDH1A1 (0.47) | TSHRALDH1A1 | |
| SCHEMBL28010889 | 0.67 | — | — | |
| SCHEMBL27842795 | 0.67 | — | — | |
| SCHEMBL17078105 | 0.67 | — | — | |
| SCHEMBL20504237 | 0.66 | — | — | |
| SCHEMBL27842797 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110870-A | SELECTIVE HERBICIDE FOR KILLING WEEDS BUT NOT OF A WHEAT, CORN OR SOYBEAN CROP, COMPOUNDS SUCH AS 1-(4-CYANO-2,5-DIFLUORO-PHENYL)-3,6-DIHYDRO-2,6-DIOXO-3-ETHYL-4 -TRIFLUOROMETHYL-1(2H)-PYRIMIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |