Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL6378781 | 1.00 | LMNA (0.59) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL8163558 | 1.00 | LMNA (0.59) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL19327501 | 1.00 | LMNA (0.59) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Didecyldimethylammonium SCHEMBL997948 | 1.00 | LMNA (0.59) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Didecyldimethylammonium SCHEMBL8384770 | 0.96 | LMNA (0.54) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Cetrimonium SCHEMBL7885553 | 0.93 | LMNA (0.57) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL8149431 | 0.93 | LMNA (0.57) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL11442866 | 0.92 | LMNA (0.50) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL6379267 | 0.92 | LMNA (0.50) | LMNADNM1HTTPDE4AHSP90AA1 | |
| Gluconic Acid SCHEMBL998503 | 0.89 | LMNA (0.53) | LMNADNM1HTTPDE4AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087303-A | METAL-FREE WOOD PRESERVATIVE CONSISTS OF A BIOCIDE CONTAINING DIMETHYL-DI-C8-C12 ALKYLAMMONIUM CARBOXYLATE OR BORATE AND AN AQUEOUS SOLVENT | LONZA, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| US-5891921-A | WOOD PRESERVATIVE SYSTEMS COMPRISING BIOCIDAL EFFECTIVE AMOUNT OF QUATERNARY AMMONIUM CARBOXYLATE, ALKYL QUATERNARY AMMONIUM BORATE, AND SOLVENT | LONZA INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5700841-A | WOOD PRESERVATIVES | LONZA INC. (US) | 1997-12-23 | — | — | US | disclosed |
| US-5641726-A | WOOD PRESERVATIVES | LONZA, INC. (US) | 1997-06-24 | — | — | US | disclosed |