SCHEMBL8155682

SCHEMBL8155682

C=C(CCOC(F)(F)C(F)(F)C(F)(F)C(C)(F)F)OC(=C)CCOC(F)(F)C(F)(F)C(F)(F)C(C)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6809638 0.88
SCHEMBL8161221 0.86
SCHEMBL8155732 0.78
SCHEMBL3838367 0.74
SCHEMBL21174453 0.73 MAPK1 (0.32)
SCHEMBL932194 0.71
SCHEMBL4554700 0.70
SCHEMBL9949198 0.66
SCHEMBL15671244 0.64 APP (0.32)
SCHEMBL4444950 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1049659-A1 FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME AlliedSignal Inc. (US) 2000-11-08 EP disclosed
US-6133472-A OXYVINYL GROUPS SEPARATED FROM FLUORINE CONTAINING GROUPS BY AT LEAST ONE ALKYLENE GROUP HAVING 2-8 CARBON ATOMS AND BY AT LEAST ONE OXYGEN ATOM IN ADDITION TO THE OXYGEN ON THE OXYVINYL; READILY RADIATION CURABLE ALLIEDSIGNAL INC. (US) 2000-10-17 US disclosed
WO-1999036381-A1 FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME ALLIEDSIGNAL INC. (US) 1999-07-22 WO disclosed