Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | SNCA | P37840 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467250 | 0.91 | SNCA (0.50) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL28470729 | 0.91 | SNCA (0.50) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11580945 | 0.90 | NOX1 (0.77) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL2706291 | 0.88 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL27477204 | 0.87 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL885358 | 0.85 | NOX1 (0.57) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL2756739 | 0.82 | NOX1 (0.50) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL22960441 | 0.82 | NOX1 (0.65) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL22960495 | 0.81 | NOX1 (0.68) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL885286 | 0.79 | NOX1 (0.50) | NOX1MAPTGAASNCAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57115435-A | — | — | None | — | — | JP | disclosed |
| EP-2998303-B1 | PHENOTHIAZINE DERIVATIVES AND METHODS FOR TREATING TUMORS | B & G PARTNERS LLC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2998303-A1 | PHENOTHIAZINE DERIVATIVES AND METHODS FOR TREATING TUMORS | B & G Partners, LLC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9198916-B1 | Compounds and methods for treating tumors | B&G PARTNERS, LLC (US) | 2015-12-01 | — | — | US | disclosed |
| JP-2000191643-A | STABILIZATION OF ALDEHYDE PYRIDINES | KOEI CHEM CO LTD | 2000-07-11 | — | — | JP | disclosed |
| JP-S57115435-A | DEGRADATION PREVENTIVE AGENT | SUMITOMO CHEM CO LTD | 1982-07-17 | — | — | JP | disclosed |