Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156905 | 1.00 | CYP2D6 (0.50) | CYP2D6MC4RMIFKMT2AHSD11B1 | |
| SCHEMBL8075022 | 0.76 | ATM (0.43) | CYP2D6MC4RKMT2AHSD11B1CHRM2 | |
| SCHEMBL8075025 | 0.76 | ATM (0.43) | CYP2D6MC4RKMT2AHSD11B1CHRM2 | |
| SCHEMBL4515174 | 0.69 | KMT2A (0.58) | CYP2D6MC4RKMT2AHSD11B1OPRM1 | |
| SCHEMBL3105377 | 0.69 | MIF (0.47) | CYP2D6MIFHSD11B1ALDH1A1POLB | |
| SCHEMBL3105373 | 0.69 | MIF (0.47) | CYP2D6MIFHSD11B1ALDH1A1POLB | |
| SCHEMBL16226061 | 0.68 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL6706135 | 0.68 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL7264542 | 0.68 | CYP2D6 (1.00) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL10035309 | 0.67 | CYP2D6 (0.54) | CYP2D6MC4RKMT2AHSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000198774-A | OPTICALLY ACTIVE GUANIDINE DERIVATIVE | SHIRATORI SEIYAKU KK | 2000-07-18 | — | — | JP | disclosed |