Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651571 | 0.88 | CYP2D6 (0.47) | CYP2D6MC4RALDH1A1POLBKMT2A | |
| SCHEMBL16525749 | 0.77 | HPGD (0.37) | CYP2D6ALDH1A1OPRM1HSD17B10KDM4E | |
| SCHEMBL5847681 | 0.75 | SLC6A2 (0.54) | CYP2D6MC4RALDH1A1KMT2AOPRM1 | |
| SCHEMBL5355369 | 0.75 | CYP2D6 (0.74) | CYP2D6MC4RALDH1A1POLBKMT2A | |
| Bromide SCHEMBL28911957 | 0.75 | HPGD (0.36) | CYP2D6ALDH1A1OPRM1HSD17B10KDM4E | |
| Bicarbonate SCHEMBL22393229 | 0.72 | ALOX15 (0.40) | CYP2D6POLBKMT2AHPGD | |
| SCHEMBL5848884 | 0.72 | SLC6A2 (0.45) | CYP2D6MC4RALDH1A1POLBKMT2A | |
| SCHEMBL5848485 | 0.72 | SLC6A2 (0.56) | CYP2D6MC4RALDH1A1POLBKMT2A | |
| SCHEMBL12846188 | 0.71 | CYP2D6 (0.56) | CYP2D6MC4RALDH1A1POLBKMT2A | |
| SCHEMBL20034096 | 0.71 | CYP2D6 (0.56) | CYP2D6MC4RALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088346-B2 | Alkene hydrofunctionalization reactions | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | ADH1A, ADH1C, ADH5 | CYP2D6 262/4885MC4R 4816/4885ALDH1A1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.