Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194484 | 1.00 | PTPN1 (0.53) | PTPN1LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL7189695 | 0.91 | PTPN1 (0.53) | PTPN1LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL8153542 | 0.88 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL7193361 | 0.88 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL7191594 | 0.78 | PTPN1 (0.45) | PTPN1ALDH1A1TSHRPDE4B | |
| SCHEMBL8157061 | 0.78 | PTPN1 (0.45) | PTPN1ALDH1A1TSHRPDE4B | |
| SCHEMBL4851044 | 0.77 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL27002063 | 0.74 | HTR2A (0.56) | LMNAHPGDKDM4EALDH1A1TSHR | |
| SCHEMBL27001993 | 0.74 | HTR2A (0.56) | LMNAHPGDKDM4EALDH1A1TSHR | |
| SCHEMBL7774653 | 0.74 | THRA (0.42) | PTPN1HPGDALOX5PTGS2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |