SCHEMBL8157124

SCHEMBL8157124

CCCCCCCCCCCCCCCCc1ccccc1-c1ccccc1CCCCCCCCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.62
NR1H2 P55055 1/20 0.59
NR1H3 Q13133 1/20 0.59
GPR3 P46089 1/20 0.50
PTPN1 P18031 1/20 0.49
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2A Q92830 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT5 Q92993 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
KCNH2 Q12809 1/20 0.47
CYSLTR2 Q9NS75 4/20 0.46
CYSLTR1 Q9Y271 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619382 1.00 LIPG (0.62) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL196217 1.00 LIPG (0.62) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL1921650 1.00 LIPG (0.62) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL1414266 1.00 LIPG (0.62) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL11663988 1.00 LIPG (0.62) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL1024526 0.98 LIPG (0.59) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL2701240 0.91 LIPG (0.50) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL28915247 0.90 LIPG (0.53) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL27999695 0.90 LIPG (0.53) LIPGNR1H2NR1H3GPR3PTPN1
SCHEMBL984108 0.89 LIPG (0.56) LIPGNR1H2NR1H3BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000018707-A1 ALKYLATION OF AROMATIC COMPOUNDS WITH α-OLEFINS USING ZEOLITE CATALYSTS SOLUTIA INC. (US) 2000-04-06 WO disclosed
EP-0446301-A1 PREPARATION OF BIARYL COMPOUNDS. EASTMAN KODAK CO (US) 1991-09-18 EP disclosed
WO-1990006295-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1990-06-14 WO disclosed