Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609328 | 0.93 | POLB (0.59) | POLBLTA4HKMT2A | |
| SCHEMBL8806149 | 0.85 | POLB (0.58) | POLBLTA4HKMT2A | |
| SCHEMBL8714251 | 0.84 | LTA4H (0.45) | POLBLTA4HCHRNB4CHRNA3 | |
| SCHEMBL4663020 | 0.81 | LTA4H (0.60) | POLBLTA4HCHRNB4CHRNA3 | |
| SCHEMBL3330017 | 0.81 | LTA4H (0.60) | POLBLTA4HCHRNB4CHRNA3 | |
| SCHEMBL12487100 | 0.81 | LTA4H (0.60) | POLBLTA4HCHRNB4CHRNA3 | |
| SCHEMBL6251075 | 0.81 | CHRNB4 (0.41) | POLBLTA4HCHRNB4CHRNA3 | |
| SCHEMBL12371288 | 0.79 | CYP2D6 (0.36) | POLBLTA4HKMT2ACHRNB4CHRNA3 | |
| SCHEMBL6612536 | 0.78 | LTA4H (0.50) | POLBLTA4H | |
| SCHEMBL3495293 | 0.78 | LTA4H (0.51) | POLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021397-A4 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC (US) | 2000-10-04 | — | — | EP | disclosed |
| EP-1021397-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998039287-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |