SCHEMBL815748

SCHEMBL815748

Fc1cc(F)c(OCCCOc2c(F)cc(F)cc2I)c(I)c1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15781965 0.98 FFAR4 (0.30)
SCHEMBL16333319 0.89 SCN8A (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16339812 0.89
SCHEMBL16333705 0.87 F2 (0.34)
SCHEMBL16339985 0.86
SCHEMBL28601432 0.86 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16333603 0.83 SCN8A (0.30)
SCHEMBL16340047 0.81 TRPA1 (0.35)
SCHEMBL816988 0.80 CCNB2 (0.32)
SCHEMBL814826 0.80 SCN8A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3925989-B1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-07 EP disclosed
EP-3013871-B1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-19 EP disclosed
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP disclosed
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP disclosed
US-10144791-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-04 US disclosed
US-20170158790-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2017-06-08 US disclosed
US-20170158790-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2017-06-08 US disclosed
US-20170158790-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2017-06-08 US disclosed
US-9605098-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-28 US disclosed
US-9605098-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-28 US disclosed
US-8609794-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES, LLC. (US) 2013-12-17 US disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
EP-2491062-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2012-08-29 EP disclosed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 GRIN2D 4641/4885GRIN3B 3312/4885GRIN1 2285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.