SCHEMBL8157485

SCHEMBL8157485

CC1=C(C2=C(C)C=CC2C)C(C)C=C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33
RELA Q04206 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280458 0.75
Hydrochloric Acid SCHEMBL4067791 0.69 NFKB1 (0.30) NFKB1NFKB2RELA
Hydrochloric Acid SCHEMBL12815602 0.69 NFKB1 (0.30) NFKB1NFKB2RELA
Hydrochloric Acid SCHEMBL7197100 0.69 NFKB1 (0.30) NFKB1NFKB2RELA
Hydrochloric Acid SCHEMBL7197097 0.69 NFKB1 (0.30) NFKB1NFKB2RELA
SCHEMBL8731614 0.64
Hydrochloric Acid SCHEMBL6909118 0.64
SCHEMBL14559790 0.63
SCHEMBL4941650 0.63
Hydrochloric Acid SCHEMBL718345 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716092-B1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORP (JP) 2000-10-25 EP disclosed
US-5770666-A METALLOCENE TOSOH CORPORATION (JP) 1998-06-23 US disclosed
EP-0716092-A1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORPORATION (JP) 1996-06-12 EP disclosed