Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163857 | 0.95 | PIK3CD (0.56) | PIK3CDGRM2KDM4EPER2CRY2 | |
| SCHEMBL8157457 | 0.88 | KDM4E (0.43) | PIK3CDGRM2KDM4EPER2CRY2 | |
| SCHEMBL21990966 | 0.77 | PIK3CD (0.46) | PIK3CDGRM2KDM4EPER2CRY2 | |
| SCHEMBL12251950 | 0.75 | PIK3CD (0.59) | PIK3CDGRM2KDM4EPER2CRY2 | |
| SCHEMBL19185719 | 0.75 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL4874421 | 0.74 | PIK3CD (0.43) | PIK3CDGRM2KDM4E | |
| SCHEMBL24909657 | 0.73 | PIK3CD (0.89) | PIK3CDGRM2KDM4EPER2CRY2 | |
| SCHEMBL8516440 | 0.71 | PIK3CD (0.54) | PIK3CDGRM2KDM4E | |
| SCHEMBL6360878 | 0.71 | — | — | |
| SCHEMBL8272699 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086905-A | Topical compositions useful as skin penetration barriers | DISCOVERY THERAPEUTICS, INC. | 2000-07-11 | — | — | US | disclosed |